Endometrial cancer is a cancer that starts in the endometrium, the inner lining of the uterus. Nearly all cancers of the uterus start in the endometrium and are called endometrial carcinomas. Cancers can also start in the muscle layer or supporting connective tissue of the uterus. These cancers belong to the group of cancers called sarcomas. Click here for information about Uterine Sarcoma, a much less common disease.
Endometrial Cancer usually develops slowly and most often occurs in post-menopausal women.
In the United States, cancer of the endometrium is the most common gynecologic cancer. The American Cancer Society estimates that in 2012 about 47,130 new cases of cancer of the body of the uterus will be diagnosed, and about 8,010 women will die from cancers of the uterine body.
These estimates include both endometrial cancers and uterine sarcomas.
About 2% of uterine body cancers are sarcomas, so the actual numbers for endometrial cancer cases and deaths are slightly lower than these estimates.