George Coukos, M.D., Ph.D
Professor, Division of Gynecologic Oncology
Department of Obstetrics and Gynecology, University of Pennsylvania
Director, Penn Ovarian Cancer Research Center
George Coukos, M.D., Ph.D, is a Professor in the Division of Gynecologic Oncology and also directs the Gynecologic Malignancy Research Program at the University of Pennsylvania. He earned an M.D. (cum laude) from the University of Modena (Italy), and a Ph.D. (Reproductive Biology) from the University of Patras School of Medicine (Greece). He completed his Obstetrics and Gynecology residency and a clinical fellowship in Gynecologic Oncology at the University of Pennsylvania and is Board-certified in both. Dr. Coukos also served as Director of Gynecology Service at the Veteran’s Administration Hospital in Philadelphia. In 2005, Dr. Coukos was appointed the Celso Ramon Garcia Chair in Reproductive Biology, and in 2007 the Center for Research on the Early Detection and Cure of Ovarian was established with Dr. Coukos as its Director.
Dr. Coukos is best known for his effort and contributions in translational research on understanding the immune system’s response to ovarian cancer. Dr. Coukos’ findings provide the first proof that a spontaneous immune response against the tumor dramatically impacts the clinical course of ovarian cancer. His current research interests focus on three areas that evolve around the overarching theme of the tumor microenvironment: (1) Tumor immune surveillance and tolerance. (2) Immune-vascular interactions. (3) Microenvironment editing by tumor cells. Dr. Coukos is currently involved in preclinical research focused on the development and optimization of combinatorial biological therapies and is involved in clinical trials testing immune therapies against ovarian cancer.
Dr. Coukos’s contributions to Ovarian Cancer have been widely acknowledged with awards from academia and technical and professional societies. He is the recipient of many awards and honors, most notably the ABOG Scholar, American Association of Obstetricians and Gynecologists Foundations (2001), Bristol-Myers Immunology-Oncology Award, Gynecologic Cancer Foundation (2002), Translational Science Award, Sidney Kimmel Foundation (2003), Schwid Award, Gynecologic Cancer Foundation (2003), Liz Tiberis Award, Ovarian Cancer Research Fund (2003), Mary Kay Ash Foundation Award (2004), Greenfield Award for “Excellence in Ovarian Cancer Research”, Gynecologic Cancer Foundation (2006), Judah Folkman Award, Alliance for Cancer Gene Therapy (2006), Sir William Osler Award for Excellence in Patient Oriented Research, University of Pennsylvania (2007), and the Philadelphia Crystal Ball Award for Research Excellence in Ovarian Cancer.
Dr. Coukos is involved in numerous collaborations bridging academia, industry and federal institutions in the interest of research. His laboratory is funded by the NIH, DOD, private foundations and Industry. He has authored and co-authored numerous technical publications and books. He is a member of the Developmental Therapeutics Committee and the Committee on Experimental Medicine of the Gynecologic Oncology Group, and has functioned as ad-hoc reviewer of various NIH and DOD study sections as well as various scientific journals.