Ie-Ming Shih, M.D., Ph.D.

Ie-Ming Shih JHED photoProfessor
Departments of Pathology, Oncology and Gynecology/Obstetrics
Johns Hopkins University School of Medicine

Dr. Shih is a Professor of Pathology, Gynecology/Obstetrics and Oncology at the Johns Hopkins University School of Medicine, Baltimore, Maryland. He is a board-certified attending pathologist in the Division of Gynecologic Pathology at the Johns Hopkins Hospital. Dr. Shih obtained his MD degree from the Taipei Medical University, Taiwan, and received his PhD in biomedical studies at the University of Pennsylvania. He completed residency training in Anatomic Pathology followed by a Gynecologic Pathology fellowship at the Johns Hopkins Hospital. He spent two post-doctoral years in the laboratory of Bert Vogelstein studying molecular cancer genetics. Dr. Shih was appointed to the faculty of Johns Hopkins in 2000 and became a professor in 2008. Dr. Shih’s research focus is on the molecular pathogenesis of gynecologic diseases, especially the basic and translational research in ovarian cancer. His ovarian cancer research team has applied genome-wide analysis, and molecular and cellular biologic techniques along with various animal models to elucidate the molecular etiology and pathogenesis of chemoresistance in ovarian and, most recently, uterine cancer. His molecular genetic studies in different types of ovarian carcinoma have helped define the dualistic pathway in the development of ovarian cancer. Recently, Dr. Shih’s team has studied the molecular features that characterize serous tubal intraepithelial carcinoma, a presumable precursor of most high-grade ovarian serous carcinomas.  Dr. Shih’s research is primarily supported by NIH/NCI and Department of Defense Ovarian Cancer Research Program.  He is the Editor-in-Chief of Current Obstetrics and Gynecology Report and serves as an editorial board member in several journals including Cancer Research and Journal of Pathology.