News

Maintenance Pazopanib in Ovarian Cancer: No Survival Benefit, High Rate of Complications

(Sept. 25, 2014) Maintenance therapy with the oral agent pazopanib improved progression free survival (PFS) by a median of 5.6 months in patients with advanced ovarian cancer but did not impact overall survival, according to the results of a phase III randomized trial reported in the Journal of Clinical... 

OCRF Research Finds Metastasis Promoted by Mesothelial Cells

Ernst Lengyel, MD, PhD A new study in the Journal of Clinical Investigation indicates that mesothelial cells actively promote the spread of ovarian cancer. Using a three dimensional culture model of ovarian cancer metastasis, OCRF grantee and Scientific Advisory Committee Member Ernst Lengyel, MD, PhD,... 

Ovarian Cancer Dream Team Call for Ideas Now Open

The American Association for Cancer Research is now accepting submissions of ideas for the new Stand Up To Cancer Ovarian Cancer Translational Research Dream Team Grant that will offer up to $6 million in research funding, which includes $3 million provided by the leading funder, OCRF. The Stand Up... 

New Study Shows No Association between Powder Use and Ovarian Cancer

(September 12, 2014) A new study published in the Journal of the National Cancer Institute this month suggests that use of perineal powder does not influence ovarian cancer risk. In the past, some studies have suggested that there is an increased risk of ovarian cancer among talc users.  In this new... 

New Stand Up To Cancer Ovarian Cancer Dream Team Announced

Ovarian Cancer Community Joins Forces to Fight Deadliest Gynecologic Cancer A groundbreaking collaboration among three national ovarian cancer organizations was announced during the Stand Up to Cancer telecast on Friday evening, September 5th. Ovarian Cancer Research Fund (OCRF), Ovarian Cancer National... 

Where There’s a Wheel, There’s a Way: Ovarian Cycle Founder, Bethany Diamond

Bethany Diamond When acclaimed fitness instructor Bethany Diamond created the very first Ovarian Cycle ride in Atlanta in 2004, she couldn’t have known that a decade later, Ovarian Cycle would become part of OCRF and thousands of participants across the country would have helped raise over $2... 

Statin Therapy and Improved Survival in Some Ovarian Cancer Patients

(September 2, 2014) New research by researchers at the University of Chicago, including OCRF grantee and Scientific Advisory Committee member Ernst Lengyel, MD, PhD, investigated whether statin use is associated with improved epithelial ovarian cancer (OvCa) survival.  The findings were published this... 

Dietary Fat Intake and Risk of Epithelial Ovarian Cancer

(August 27, 2014) Recent research published in Cancer Epidemiology suggests that there is “no association with consumption of total fat, animal or plant fat, saturated fat, cholesterol, monounsaturated fat, or fatty fish and risk of invasive epithelial ovarian cancer.” An international team of researchers... 

New Report Recommends Classifying Cancer by Genetic and Molecular Type

(August 21, 2014) A research network in the US proposes that cancer should be classified according to genetic and molecular features rather than by the type of tissue in which the tumor arises. While more work is needed to confirm and build on the findings, the scientists say such a system would be better... 

Drug Combination Impacts Outcomes in Ovarian Cancer Patients without BRCA Mutations

Ron Buckanovich, MD, PhD BRCA mutations in ovarian cancer are a double-edged sword.  While BRCA gene mutation carriers have a significantly higher risk of developing ovarian cancer, BRCA gene mutation in tumors is associated with a significant increase in patient survival.  Scientists believe that...