OCRF & Ovarian Cancer National Alliance are now one strong, united, inspiring voice!
Ovarian Cancer Research Fund (OCRF) and the Ovarian Cancer National Alliance (OCNA) have led the way in advocacy, research and support for patients and their families for over 22 years. As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Fund Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families. Read the exciting news!

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OCRF Research Offers Insight on How Ovarian Cancer Grows

Ron Buckanovich, MD, PhD (December 1, 2015) Research funded in part by Ovarian Cancer Research Fund, and published in PNAS, offers new insights into how ovarian cancer grows—and the potential to stop it. Can any cancer cell form another tumor, or is it only select cancer stem cells that give rise to... 

Better Outcomes for Ovarian Cancer Patients with History of Oral Contraceptive Use

(November 20, 2015) A study published in BMC Cancer demonstrates that ovarian cancer patients who had a history of oral contraceptive use had better outcomes than those who had not previously used them. Dr. Aminah Jatoi and co-author Dr. Ellen Goode, both of the Mayo Clinic, examined 1,398 cases during... 

Ten-year Survival Not Associated with BRCA Mutation Status

(Nov. 19, 2016) In research published this month in Gynecologic Oncology, a group of Canadian researchers have found that long-term survival is not associated with BRCA mutation status in ovarian cancer patients. Past research has shown that after a diagnosis of ovarian cancer, positive BRCA mutation... 

Meet OCRF’s 2016 Grantees

(Nov. 17, 2015) Ovarian Cancer Research Fund has announced that $5.2 million has been awarded in scientific research grants for ovarian cancer. This brings OCRF’s total investment in research to nearly $70 million. OCRF’s 2016 grants have been awarded to eighteen top scientists at thirteen leading... 

OCRF Research Explains Limits of Cancer Immunotherapy Drugs

Weiping Zou, MD, PhD A new study of ovarian cancer cells from the University of Michigan Comprehensive Cancer Center, funded in part by an OCRF grant to Dr. Weiping Zou, reveals molecular changes within the tumor that prevent immunotherapy drugs from killing off the cancer.  The research was published... 

BRCA Mutations Confer Risk, Even in Absence of Family History

(October 15, 2015)  According to a Japanese study published in Cancer, BRCA1/2 gene mutations may be associated with an inherited risk of ovarian cancer regardless of family history. The researchers examined 95 women with ovarian cancer who were treated from 2013 to 2015.  BRCA1/2 gene mutation... 

Most Women Getting BRCA Test not Getting Genetic Counseling

(October 7, 2015) A report published in JAMA Oncology shows that most commercially insured women who underwent BRCA genetic testing did not receive genetic counseling by trained genetics professionals.  Lack of clinician recommendation was the most commonly reported reason why they didn’t receive... 

Hormone Replacement Therapy Beneficial to Ovarian Cancer Patients

(October 1, 2015) A new study published in the Journal of Clinical Oncology shows that women with the most common type of ovarian cancer can safely take hormone replacement therapy (HRT), and it could have a beneficial effect on their survival. The 24-year, phase III international trial provides the... 

Small Trial Shows Promising Results for Nivolumab in Ovarian Cancer

(September 21, 2015) A small study found that treatment with the anti-PD-1 immunotherapy nivolumab was able to produce complete responses in patients with advanced platinum-resistant ovarian cancer. The phase II study of 20 patients had an overall response rate of 15% (3 responders); an additional 6... 

Q&A with OCRF Grantee Kris Wood, PhD

Kris Wood, PhD Q&A with Kris Wood, PhD Duke University 2014 Liz Tilberis Award   OCRF: Tell me about yourself. Kris Wood: I grew up in Georgetown, KY, a rural town in the central part of the state. My family lived in a house on my grandfather’s farm, which was a wonderful place to grow up–...