News

OCRF Educational Webinar Series Presentations Available

Over the course of each year, OCRF offers free educational webinars on topics related to ovarian cancer and ovarian cancer research.  You can view and listen to archived copies of these presentations below. 2013 Exploring the Origins of Ovarian Cancer Presented by Ronny Drapkin, MD, PhD, Assistant Professor... 

Q&A with Ron Chandler, Ph.D.

Dr. Ron Chandler is a 2013 Ann Schreiber Mentored Investigator Award recipient. In this interview with OCRF’s Sarah DeFeo, Dr. Chandler discusses his research and what it means to receive a grant from OCRF. Sarah DeFeo:  Tell us about yourself. Ron Chandler:  I am the first Ph.D. scientist... 

Q&A with Maria Barbolina, Ph.D.

Dr. Maria Barbolina is a 2013 Liz Tilberis Early Career Award grant recipient. In this interview with OCRF’s Sarah DeFeo, Dr. Barolina discusses her research and what it means to receive a grant from OCRF. Sarah DeFeo:  Tell us a little about yourself. Maria Barbolina:  I live in Chicago... 

OCRF Researchers Find Some Immune Cells Aid Cancer Growth

A new OCRF-funded study from researchers at the University of Michigan Comprehensive Cancer Center found that a subset of immune cells, called myeloid derived suppressor cells, do more harm than good by providing a niche where the cancer stem cells survive.  The research is published in the journal... 

Helq Gene Increases Risk of Rare Ovarian Cancer

Researchers in the UK have identified a gene in mice that, if faulty, may increase the chance of developing a rare type of ovarian cancer.  The findings were published in the journal Nature. The gene, known as Helq, helps repair damage to DNA that happens when it is copied as cells multiply. If the... 

Promising New Approach for Early Detection of Ovarian Cancer

Building on previously presented work, researchers at M.D. Anderson Cancer Center in Houston have published new findings that show that evaluating the change of CA-125 over time shows promise as a screening tool for early-stage ovarian cancer. OCRF grantees Karen Lu, MD and Robert Bast, MD were first... 

OCRF Researchers Review Preclinical Models Used in Ovarian Cancer Research

In a review article published online in Oncogene on August 12, OCRF-funded researchers provide a comprehensive review of pre-clinical models used in ovarian cancer research.  The authors, including OCRF grantees Ernst Lengyel, Daniela Matei, Ken Nephew, and Joanna Burdette, explore current experimental... 

Time Interval from Surgery to Chemo Impacts Prognosis in Ovarian Cancer

Researchers in Austria investigated whether the time interval from surgery to start of chemotherapy has an impact on clinical outcome in patients with advanced serous ovarian cancer. Data from 191 patients with stage III or IV ovarian cancer who underwent surgery followed by platinum-based chemotherapy... 

Analysis Points to New Cell Lines as Tumor Models for Ovarian Cancer Research

Research published online last week in Nature Communications suggests that some of the cell lines most frequently used to study high-grade serous ovarian cancer (HGSOC) may not be the best.  OCRF grantee and SAC member Douglas Levine, MD was one of the authors of the paper. Cell lines derived from tumor... 

Progesterone and Estrogen Receptors are Prognostic Biomarkers for Some Ovarian Cancers

In an article published last week in The Lancet, an international group of investigators examined whether ovarian cancer tumors’ expression of the progesterone receptor (PR) and estrogen receptor (ER) was associated with survival in various subtypes of ovarian cancer.  To date, few biomarkers of...