Research News

Palliative Care at Time of Cancer Diagnosis Improves Survival

(June 25, 2014) Research presented at the annual meeting of the American Society of Clinical Oncology earlier this month suggests that palliative care delivered at the time of cancer diagnosis improves survival. A randomized trial of palliative oncology care in 207 patients with advanced cancer and their... 

Gemcitabine, Carboplatin, and Bevacizumab Extend PFS

(June 24, 2014) Earlier this month, researchers reported results of a Phase II trial which looked at efficacy and safety of a biweekly gemcitabine, carboplatin, and bevacizumab combination in patients with platinum-sensitive recurrent ovarian, peritoneal, or tubal cancer. The results, which were published... 

Webinar Highlights Research News from ASCO

On Monday, June 16, 2014, Dr. Douglas Levine of Memorial Sloan Kettering Cancer Center presented a free webinar focusing on research  news that was presented at 2014′s medical meetings.  In his hour-long presentation, he focused primarily on new ovarian cancer research that was presented at the... 

ASCO News: Two New Drugs Show Promise for Recurrent Ovarian Cancer

(June 4, 2014) In a study presented at the American Society of Clinical Oncology annual meeting last week, researchers found that the combination of olaparib and cediranib (Recentin) kept recurrent ovarian cancer from worsening for almost nine months longer than treatment with olaparib alone. For this... 

FDA Seeking Comments on Olaparib by June 11

The Food and Drug Administration is seeking comments by June 11, 2014 on its review for Olaparib approval. Olaparib is an oral poly ADP-ribose polymerase (PARP) inhibitor that exploits DNA repair pathway deficiencies to preferentially kill cancer cells.  AstraZeneca, the company that manufactures the... 

Breastfeeding, Birth Control Pills May Reduce Ovarian Cancer Risk Among Women with BRCA Gene Mutations

(May 16, 2014) Breastfeeding, tubal ligation – also known as having one’s “tubes tied” – and oral contraceptives may lower the risk of ovarian cancer for some women with BRCA gene mutations, according to a comprehensive analysis from a team at the University of Pennsylvania’s... 

OCRF Research Shows How Ovarian Tumors Elude Immune System

Greg Motz, PhD (May 6, 2014) Tumors use numerous mechanisms to escape detection and killing by the immune system. Results from OCRF-funded research, reported May 4, 2014 in the prestigious journal Nature Medicine, show that ovarian cancer cells (and others) establish a protective barrier that prevents... 

Imaging Predicts Response in Ovarian Cancer

(April 30, 2014) A positive pretreatment imaging test more than doubled the likelihood of disease control in platinum-resistant advanced ovarian cancer treated with the folate receptor-targeted drug vintafolide (trade name Vynfinit), results of a small phase II study showed. The research was reported in... 

News from AACR: Irregular Menses Linked to High Risk of Ovarian Cancer

(April 15, 2014) Prolonged (>35 days), infrequent, or anovulatory menstrual cycles was associated with as much as a two-fold increase in ovarian cancer and more than a three-fold increase in the risk of fatal ovarian cancer, according to a 50-year, prospective follow-up in 14,403 women. The findings... 

Physical Activity Associated with Lower Risk of Ovarian Cancer Mortality

(April 8, 2014) A team of researchers have found that vigorous physical activity prior to ovarian cancer diagnosis was associated with a lower risk of ovarian cancer mortality.  The findings were published in Gynecologic Oncology. There is limited knowledge of the association of modifiable lifestyle...