Uncategorized

OCRF Research Identifies Fusion Gene Common in Ovarian Cancer

(April 7, 2014) A group of OCRF-funded researchers at Baylor College of Medicine have found a “fusion gene” that is present in 20% of high grade serous ovarian cancer patients.  The finding, which was published in PLOS Genetics, was supported in part by OCRF grants to Martin Matzuk, MD,... 

OCRF Research Sheds Light on Ovarian Cancer Origins in BRCA Mutation Carriers

A team of current and former OCRF grantees at Brigham and Women’s Hospital, Harvard Medical School and Dana-Farber Cancer Institute has developed genetically engineered mouse models of high-grade serous ovarian cancer that shed light on the pathogenesis of ovarian cancer for BRCA1/2 mutation carriers. ... 

New Genetic Mutation Increases Risk of Ovarian Cancer

08/17/2011 Researchers in the United Kingdom have discovered a new genetic mutation that increases the risk for ovarian cancer.  This major finding was published online in the journal Nature Genetics on August 7th. Much like the BRCA1 and BRCA2 mutations, which were discovered in the 1990s and which...