News

New Report Recommends Classifying Cancer by Genetic and Molecular Type

(August 21, 2014) A research network in the US proposes that cancer should be classified according to genetic and molecular features rather than by the type of tissue in which the tumor arises. While more work is needed to confirm and build on the findings, the scientists say such a system would be better... 

Drug Combination Impacts Outcomes in Ovarian Cancer Patients without BRCA Mutations

Ron Buckanovich, MD, PhD BRCA mutations in ovarian cancer are a double-edged sword.  While BRCA gene mutation carriers have a significantly higher risk of developing ovarian cancer, BRCA gene mutation in tumors is associated with a significant increase in patient survival.  Scientists believe that... 

Epigenetic Targeting of Ovarian Cancer Stem Cells

(July 29, 2014)   OCRF-funded research published earlier this month provides the first proof of principle that epigenomic strategies efficiently target ovarian cancer stem cells, which are key for treatment resistance and the major factor in therapy failures.  OCRF grantees Kenneth Nephew, PhD and...