Research News

SGO Perspectives on Endpoints for Studies of Ovarian Cancer

(Sept. 29, 2014) In a perspective piece for the website MedPage Today, representatives from the Society of Gynecologic Oncology discuss of clinical endpoints appropriate for studies addressing the “unique characteristics” of ovarian cancer and progress toward improving outcomes for women... 

Maintenance Pazopanib in Ovarian Cancer: No Survival Benefit, High Rate of Complications

(Sept. 25, 2014) Maintenance therapy with the oral agent pazopanib improved progression free survival (PFS) by a median of 5.6 months in patients with advanced ovarian cancer but did not impact overall survival, according to the results of a phase III randomized trial reported in the Journal of Clinical... 

OCRF Research Finds Metastasis Promoted by Mesothelial Cells

Ernst Lengyel, MD, PhD A new study in the Journal of Clinical Investigation indicates that mesothelial cells actively promote the spread of ovarian cancer. Using a three dimensional culture model of ovarian cancer metastasis, OCRF grantee and Scientific Advisory Committee Member Ernst Lengyel, MD, PhD,...