Research News

Ovarian Cancer Oncogene Found in ‘Junk DNA’

(October 6, 2014) A research team based at the University of Pennsylvania mined junk DNA sequences to identify a non-protein-coding RNA whose expression is linked to ovarian cancer.  The study, which was published in Cancer Cell, was supported in part by an OCRF research grant to Lin Zhang, MD. The... 

SGO Perspectives on Endpoints for Studies of Ovarian Cancer

(Sept. 29, 2014) In a perspective piece for the website MedPage Today, representatives from the Society of Gynecologic Oncology discuss clinical endpoints appropriate for studies addressing the “unique characteristics” of ovarian cancer and progress toward improving outcomes for women affected... 

Maintenance Pazopanib in Ovarian Cancer: No Survival Benefit, High Rate of Complications

(Sept. 25, 2014) Maintenance therapy with the oral agent pazopanib improved progression free survival (PFS) by a median of 5.6 months in patients with advanced ovarian cancer but did not impact overall survival, according to the results of a phase III randomized trial reported in the Journal of Clinical...