OCRF & Ovarian Cancer National Alliance are now one strong, united, inspiring voice!
Ovarian Cancer Research Fund (OCRF) and the Ovarian Cancer National Alliance (OCNA) have led the way in advocacy, research and support for patients and their families for over 22 years. As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Fund Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families. Read the exciting news!


2006 Ann Schreiber Grant Recipient – Ramandeep Rattan

Ramandeep Rattan, Ph.D.
Mayo Clinic
Gene May Be An Early Marker for Ovarian Cancer

Project Summary

Project Summary
Unfortunately, most ovarian cancer is detected too late and treatment options become limited. Therefore, a better understanding of early changes in ovarian cancer should allow early detection, better diagnosis and improved treatment. Dr. Rattan has used state of the art gene technology to identify early genetic changes in ovarian cancer by comparing the genetic fingerprints of early and late stage tumors. Recently, his analyses have identified a gene called TCEAL7, which his evidence suggests might be important in changing ovarian epithelial cells to cancer cells, an early step in the disease process. In his project, he is studying how TCEAL7 acts with other biochemical pathways to cause these cancerous transformations. His research might someday lead to the use of TCEAL7 as an early marker of disease or as a target for new drug treatment.