OCRF & Ovarian Cancer National Alliance are now one strong, united, inspiring voice!
Ovarian Cancer Research Fund (OCRF) and the Ovarian Cancer National Alliance (OCNA) have led the way in advocacy, research and support for patients and their families for over 22 years. As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Fund Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families. Read the exciting news!


2007 Ann Schreiber Grant Recipient – Mitchell Cheung

Mitchell Cheung, Ph.D.
Fox Chase Cancer Center
Testing New Therapeutic Agents to Treat Ovarian Cancer

Project Summary

Dr. Cheung is researching new types of drugs that are designed to deactivate two molecular pathways, called AKT and PAK, which are believed to make ovarian cancers particularly aggressive. In his project, he will target these two pathways with small molecule inhibitors to test whether administration of two or more of these agents can be more effective than a single agent in ovarian cancer therapy. Initially, he will use cells grown in culture to identify the optimal drug combinations and drug concentrations. Studies in mice will then be used to further evaluate our proposed treatment regimen.