OCRF & Ovarian Cancer National Alliance are now one strong, united, inspiring voice!
Ovarian Cancer Research Fund (OCRF) and the Ovarian Cancer National Alliance (OCNA) have led the way in advocacy, research and support for patients and their families for over 22 years. As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Fund Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families. Read the exciting news!


2003 Individual Investigator Grant Recipient – Changping Zou

Changping Zou, M.D., Ph.D.
University of Arizona
Finding Biomarkers for Early Detection of Ovarian Cancer

Project Summary

The objective of the proposed study is to identify biomarkers that can be used for early detection of ovarian cancer and for assessing the efficacy of chemoprevention agents that could potentially stop the disease from occurring. The biomarkers will be selected through searching for genes with expression changes in normal, pre-cancer, and ovarian cancer cells, and those which can be altered by chemopreventive agents. Dr. Zou will establish a molecular profile for the normal, immortalized (as a pre-cancer model) and malignant ovarian epithelial cells (as a cancer model) and characterize the in vitro responses of normal, immortalized, and malignant ovarian epithelial cells to a chemopreventive agent and verify the biomarkers in high-risk patient sample.


Dr. Zou is now an Associate Professor, Molecular, Microbial and Structural Biology, Department of Obstetrics/Gynecology, Gynecology/Oncology at the University of Connecticut.