OCRF & Ovarian Cancer National Alliance are now one strong, united, inspiring voice!
Ovarian Cancer Research Fund (OCRF) and the Ovarian Cancer National Alliance (OCNA) have led the way in advocacy, research and support for patients and their families for over 22 years. As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Fund Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families. Read the exciting news!


2004 Individual Investigator Grant Recipient – Shu-Wing NG

Shu-Wing Ng, Ph.D.
Brigham and Women’s Hospital
Studying Membrane Proteins for Early Diagnosis and Disease Progression in Ovarian Cancer

Project Summary

Proteins on the surfaces of cell membranes move chemicals in and out of cells, transfer information between cells and their environment, and play crucial roles in many cellular and physiological processes. Dr. Ng is hoping to find cell surface proteins present at high levels in ovarian tumors to serve as possible markers for early detection of the disease. In order to identify these ovarian cancer cell surface markers, Dr. Ng proposes to employ an innovative high-throughput two-dimensional ProteomLab PF2D system to fractionate and compare the membrane proteins from normal human ovarian cells and tumor cells. The system allows detection of proteins of low abundance, which may have physiological importance and be possible markers. Novel antibodies specific to the identified cancer markers also can be developed for diagnostic and therapeutic purposes, and may thereby improve the overall survival of ovarian cancer patients.