OCRF & Ovarian Cancer National Alliance are now one strong, united, inspiring voice!
Ovarian Cancer Research Fund (OCRF) and the Ovarian Cancer National Alliance (OCNA) have led the way in advocacy, research and support for patients and their families for over 22 years. As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Fund Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families. Read the exciting news!


2005 Individual Investigator Grant Recipient – Min Zhu

Min Zhu, Ph.D.
UCLA School of Medicine
A Protein’s Possible Role in Ovarian Cancer Metastasis

Project Summary

More than 85 percent of ovarian cancers are epithelial, and the majority of patients with epithelial ovarian cancer are diagnosed with tumor metastases. Metastasis is the main reason for cancer recurrence. Therefore, identifying the genes responsible for metastasis may provide the potential targets for novel and more efficient treatment for this disease. Dr. Zhu has identified a protein called peroistin that is overexpressed in ovarian cancer-derived epithelial cells. This protein promoted tumor growth and increased blood vessel formation near the tumor. In the project, Dr. Zhu plans to study how peroistin leads to metastasis and how an antibody against peroistin might prevent metastasis. Findings should provide insights into the mechanisms of metastasis and the design of a targeted therapy against the process.