2005 Liz Tilberis Grant and 2003 Ann Schreiber Grant Recipient – Jeremy Chien
Jeremy Chien, PhD
How Cell Shape Changes Lead to Metastasis in Ovarian Cancer
Metastasis in ovarian cancer is the main obstacle for the successful treatment of patients with ovarian cancer and the main cause of their death. Emerging evidence suggests that a disruption in the structure of the epithelial cells of the ovary leads to cancer cell metastatis. In his study, Dr. Chien will study the molecular steps involved in changing the physical structure of ovarian cancer cells. The results from this study could provide insights into biological processes underlying metastatic tumor progression, and could lead to the identification of those tumors with particularly metastatic and aggressive behavior.
Dr. Jeremy Chien is an Assistant Professor of Laboratory Medicine and Pathology at the Mayo Clinic in Rochester, MN.
The five-year survival rate for ovarian cancer has increased by only 8% in the last 30 years.
We are at a critical crossroads for supporting research into unlocking the mysteries of ovarian cancer. You can make a difference by supporting the research of the Ovarian Cancer Research Fund.
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