OCRF & Ovarian Cancer National Alliance are now one strong, united, inspiring voice!
Ovarian Cancer Research Fund (OCRF) and the Ovarian Cancer National Alliance (OCNA) have led the way in advocacy, research and support for patients and their families for over 22 years. As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Fund Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families. Read the exciting news!


2007 Liz Tilberis Grant Recipient – Deborah Altomare

Deborah Altomare, Ph.D.
University of Central Florida
Clarifying the Molecules Involved in Ovarian Cancer Growth and Progression

Project Summary

The high morbidity of ovarian cancer is largely attributed to the rapid proliferation of tumor cells that spread to multiple abdominal organs. By understanding the molecular pathways that lead to ovarian cancer growth and progression, it may be possible to stop these processes with new drugs or interventions. Dr. Altomare’s research focuses on a molecular family of molecules called AKT kinases and their role in ovarian cancer tumor growth and progression. The objective of her research is to provide an improved understanding of how the three different AKT kinases interact with other molecules in ovarian cancer cells s to facilitate tumor cell proliferation, survival and/or metastasis. Both human ovarian cancer cells and genetically defined mouse models will be used in her studies.


Dr. Deborah Altomare is an Assistant Professor at the Burnett School of Biomedical Sciences, and the Director of the Transgenic Facility at the University of Central Florida in Orlando, FL.