2012 Liz Tilberis Grant Recipient – Daniela Dinulescu, PhD
Brigham and Women’s Hospital
Modeling Serous Ovarian Carcinoma Using Genetic Markers Specific for the Distal Fallopian Tube
Dr. Dinulescu is currently an Assistant Professor at Harvard Medical School. She received her Ph.D. From Oregon Health and Science University and completed her postdoctoral studies in the field of Cancer Genetics in Dr. Tyler Jacks’ laboratory at MIT. Dr. Dinulescu’s research interests focus on cancer biology, malignancies of the gonads and reproductive tract, with a special emphasis on ovarian cancer research and endometriosis. During her postdoctoral fellowship Dr. Dinulescu developed and validated the first genetic animal models for endometrioid ovarian cancer and endometriosis that accurately recapitulate the human disease. This was regarded as an important achievement in the cancer field since mouse models of ovarian cancer, which mimic the human disease, have been extremely difficult to develop. In addition, her studies helped uncover a first genetic link between endometriosis and endometrioid ovarian cancer, which helps explain their frequent association in women, a finding that was further validated by recent clinical studies.
Visit the Dinulescu Lab website for more information.
This grant was made possible by a generous donation from Ovarian Cycle.
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